GUIDELINES FOR GENERAL PRACTITIONERS
THE MANAGEMENT OF TRANSIENT ISCHAEMIC ATTACKS

Introduction

Two large trials 1 2 have recently shown that early Carotid Endarterectomy substantially reduces the risk of stroke in patients who have experienced transient ischaemic attacks (TIAs) in the carotid

 
  Dr Usman Ahmed
MB, BS, MRCP, DCN, MA, MBA

Consultant Physician
General Medicine
Geriatric Medicine
Stroke Medicine

 
 

territory due to stenosis of more than 70%
of the arterial lumen. There is now consensus that it is important to identify early, from among those patients presenting with TIAs, those who may have a significant degree of carotid artery stenosis by using colour Duplex ultrasonography.

To ensure that the full benefit is gained in a rapid and efficient manner, an agreed protocol for "fast track" referrals is essential and has been designed in agreement with the providing hospital. General practitioners will need to be aware of the system to exploit it fully.

1 European Carotid Surgery Trialists' Collaboration Group. MRC European carotid surgery trial : interim results for symptomatic patients with severe (70-99%) or with mild stenosis (0-29%) carotid stenosis. Lancet 1991; 337 : 1235-43

2 North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomastic patients with high grade stenosis. Northern England Journal of Medicine 1991; 325 : 445-53


Referral Guidelines

All patients who have had a carotid territory TIA should be referred for investigation unless they have contraindications.

The referral should, wherever possible, be made within two weeks of the episode, to the TIA CLINIC.

The service will offer colour Duplex scan and other necessary diagnostic tests and, where appropriate, early surgical treatment (or referral for surgical treatment). It is emphasised that the primary purpose of the "fast track" scheme is to select out rapidly those patients who might benefit from early surgical intervention and manage other risk factors of stroke.

Clinical Guidelines for "Fast-Track" Referrals of TIAs

SYMPTOMS

Suitable
The following symptoms, if of less than 24 hours duration, may suggest carotid territory TIA :

Hemiparesis
Hemianaesthesia
Dysphasia
Amaurosis fugax
Dyspraxia
Spatial disorientation

Also Suitable
The following symptoms are less suggestive of carotid territory TIAs and more suggestive of vertebral territory TIAs :

Dizziness
Vertigo
Drop attacks
Confusion
Diplopia
Blackouts

NOTES
Stroke with good functional recovery is also suitable for "fast-track". Patients who respond to Aspirin are still suitable for "fast-track".

A Carotid Bruit is not important; those who do not have a bruit should still be referred.

CONTRAINDICATIONS

ABSOLUTE

Cancer
Complete stroke with poor functional recovery
Dementia
Patient unwilling to consider surgery under any circumstances

RELATIVE
Age is a relative contraindication but fit patients over the age of 75 should not be excluded.

Myocardial infarction in the last six months or unstable angina in the last six months are both relative contraindications to surgery within this period, but should still be referred.

Patients who have had a minor stroke (symptoms persisting for >24 hours) with rapid and complete/near complete neurological recovery are suitable for the fast-track system. Patients who have had a complete stroke with poor neurological recovery are not suitable for the fast-track system, but should be referred for secondary prevention ( i.e. of recurrent stroke). Patients in this group whom general practitioners think might benefit from surgery should be referred to a physician on an individual basis.

MEDICAL TREATMENT
All patients with TIA should be considered for medical treatment, which includes:

Correction of risk factors: smoking, hyperlipidaemia

Treatment of Hypertension (to achieve systolic BP of <140 mmHg)

Anti-platelet therapy (Aspirin 75 mg od), anticoagulation with Warfarin for those in atrial fibrillation, and based on more recent evidence (results of PROGRESS research), consideration for combination therapy with Perindopril 4mg od and Indapamide 2.5mg od for secondary prevention in selected patients.

CLINICIAN OFFERING A FAST-TRACK SERVICE AT NORTH MANCHESTER GENERAL HOSPITAL

DR U AHMED, Consultant Physician
Telephone 0161 720 2790
FAX 0161 720 2613

SERVICES FOR PATIENTS WITH TIA AT NORTH MANCHESTER GENERAL HOSPITAL

TIA CLINIC

REFERRAL PATHWAY